Hi, I am trying this Hicorr pipeline on the Micro-C dataset to explore cis-regulatory element interactions like E-P, E-E ... because it seems that hicorr out-performs many other algorithms when correcting the bias in short range. However, in the beta version MicroC pipeline on hicorr, there is no p value calculated for each pair of anchor contact, thus I cannot determine the dummy number for ratio calculation, according to your method in the hicorr paper. I am wondering if there is another way of calculation or I misunderstand the output of hicorr? Could you please give me some instructions? Thank you very much!
Hi, I am trying this Hicorr pipeline on the Micro-C dataset to explore cis-regulatory element interactions like E-P, E-E ... because it seems that hicorr out-performs many other algorithms when correcting the bias in short range. However, in the beta version MicroC pipeline on hicorr, there is no p value calculated for each pair of anchor contact, thus I cannot determine the dummy number for ratio calculation, according to your method in the hicorr paper. I am wondering if there is another way of calculation or I misunderstand the output of hicorr? Could you please give me some instructions? Thank you very much!