Bioinformatics | Multi-omics engineering in health
Master's degree in Bioinformatics (Université Paris-Est Créteil, UPEC). I work on RNA-seq and spatial transcriptomics analysis applied to biomedical research, most recently on macrophages in chronic kidney disease at CRI - Centre de Recherche sur l'Inflammation.
Focus: bulk & single-cell RNA-seq · spatial transcriptomics · NGS data analysis
Tools: R/RStudio · Python · DESeq2 · Seurat · cell2location · CellChat
Based in Île-de-France, France · Open to bioinformatics opportunities
LinkedIn: https://www.linkedin.com/in/richmond-koffi-344922173
spatial-analysis-macrophages-CKD: spatial transcriptomics of macrophages in chronic kidney disease — cell2location deconvolution, CellChat cell-cell communication, differential expression and co-expression analysis.
analyse-RNAseq-DESeq2: DESeq2 pipeline for bulk RNA-seq differential expression — normalization, PCA, heatmaps, volcano plots and GO enrichment.
Repartition-Cell: single-cell RNA-seq analysis (Seurat) of immune cell subsets — clustering, UMAP and cell proportion comparison.
