diff --git a/lib/internal/quic/quic.js b/lib/internal/quic/quic.js
index e6ab417ab0f..72f8187e3f3 100644
--- a/lib/internal/quic/quic.js
+++ b/lib/internal/quic/quic.js
@@ -4166,7 +4166,16 @@ class QuicSession {
     // case rather than letting it hold flow control credit.
     if (!this.#hasStreamConsumer()) {
       process.emitWarning('A new stream was received but no stream consumer callback was provided');
-      stream.destroy();
+      // When the negotiated application defines a "request rejected" code
+      // (HTTP/3: H3_REQUEST_REJECTED), reset the stream with it so the peer
+      // learns the request was not processed (RFC 9114 section 4.1.1).
+      // Other applications have no such semantic and are torn down as before.
+      const rejectedCode = getQuicSessionState(this).requestRejectedCode;
+      if (getQuicSessionState(this).streamCallbacksSupported === 1) {
+        stream.destroy(undefined, { code: rejectedCode });
+      } else {
+        stream.destroy();
+      }
       return;
     }
 
diff --git a/lib/internal/quic/state.js b/lib/internal/quic/state.js
index a41790c5202..769fee68749 100644
--- a/lib/internal/quic/state.js
+++ b/lib/internal/quic/state.js
@@ -77,6 +77,7 @@ const {
   IDX_STATE_SESSION_APPLICATION_TYPE,
   IDX_STATE_SESSION_NO_ERROR_CODE,
   IDX_STATE_SESSION_INTERNAL_ERROR_CODE,
+  IDX_STATE_SESSION_REQUEST_REJECTED_CODE,
   IDX_STATE_SESSION_MAX_DATAGRAM_SIZE,
   IDX_STATE_SESSION_LAST_DATAGRAM_ID,
   IDX_STATE_SESSION_MAX_PENDING_DATAGRAMS,
@@ -125,6 +126,7 @@ assert(IDX_STATE_SESSION_WRAPPED !== undefined);
 assert(IDX_STATE_SESSION_APPLICATION_TYPE !== undefined);
 assert(IDX_STATE_SESSION_NO_ERROR_CODE !== undefined);
 assert(IDX_STATE_SESSION_INTERNAL_ERROR_CODE !== undefined);
+assert(IDX_STATE_SESSION_REQUEST_REJECTED_CODE !== undefined);
 assert(IDX_STATE_SESSION_MAX_DATAGRAM_SIZE !== undefined);
 assert(IDX_STATE_SESSION_LAST_DATAGRAM_ID !== undefined);
 assert(IDX_STATE_ENDPOINT_BOUND !== undefined);
@@ -552,6 +554,13 @@ class QuicSessionState {
       handle, this.#offset + IDX_STATE_SESSION_INTERNAL_ERROR_CODE, kIsLittleEndian);
   }
 
+  get requestRejectedCode() {
+    const handle = this.#handle;
+    if (handle === undefined) return undefined;
+    return DataViewPrototypeGetBigUint64(
+      handle, this.#offset + IDX_STATE_SESSION_REQUEST_REJECTED_CODE, kIsLittleEndian);
+  }
+
   /** @type {number} */
   get maxDatagramSize() {
     const handle = this.#handle;
diff --git a/src/quic/application.cc b/src/quic/application.cc
index 79a3263b853..c268e2e3a63 100644
--- a/src/quic/application.cc
+++ b/src/quic/application.cc
@@ -280,6 +280,11 @@ class DefaultApplication final : public Session::Application {
     return NGTCP2_INTERNAL_ERROR;
   }
 
+  // Raw QUIC has no "request rejected" semantic; reuse the no-error code.
+  error_code GetRequestRejectedCode() const override {
+    return GetNoErrorCode();
+  }
+
   void EarlyDataRejected() override {
     // Destroy all open streams — ngtcp2 has already discarded their
     // internal state when it rejected the early data. Use the
diff --git a/src/quic/application.h b/src/quic/application.h
index dec5cffb424..ace6035a0ab 100644
--- a/src/quic/application.h
+++ b/src/quic/application.h
@@ -77,6 +77,14 @@ class Session::Application : public MemoryRetainer {
   // NGTCP2_INTERNAL_ERROR (0x1).
   virtual error_code GetInternalErrorCode() const = 0;
 
+  // The "request rejected" code is sent on RESET_STREAM when an incoming
+  // request stream is rejected without any application processing (e.g.
+  // the session has no consumer for it), so the peer learns the request
+  // was not processed. For HTTP/3 this is NGHTTP3_H3_REQUEST_REJECTED
+  // (0x10b); other applications have no such semantic and reuse the
+  // "no error" code.
+  virtual error_code GetRequestRejectedCode() const = 0;
+
   // Called after Session::Receive processes a packet, outside all callback
   // scopes. Applications can use this to handle deferred operations that
   // require calling into JS (e.g., HTTP/3 GOAWAY processing).
diff --git a/src/quic/http3.cc b/src/quic/http3.cc
index 2cf4e2d6fdd..178e4615e71 100644
--- a/src/quic/http3.cc
+++ b/src/quic/http3.cc
@@ -172,6 +172,10 @@ class Http3ApplicationImpl final : public Session::Application {
     return NGHTTP3_H3_INTERNAL_ERROR;
   }
 
+  error_code GetRequestRejectedCode() const override {
+    return NGHTTP3_H3_REQUEST_REJECTED;
+  }
+
   void EarlyDataRejected() override {
     // When 0-RTT is rejected, destroy the nghttp3 connection and all
     // open streams — ngtcp2 has discarded their internal state.
diff --git a/src/quic/session.cc b/src/quic/session.cc
index 60b27fbfa35..2266f74a127 100644
--- a/src/quic/session.cc
+++ b/src/quic/session.cc
@@ -141,6 +141,7 @@ uint64_t MaxDatagramPayload(uint64_t max_frame_size) {
   V(APPLICATION_TYPE, application_type, uint8_t)                               \
   V(NO_ERROR_CODE, no_error_code, error_code)                                  \
   V(INTERNAL_ERROR_CODE, internal_error_code, error_code)                      \
+  V(REQUEST_REJECTED_CODE, request_rejected_code, error_code)                  \
   V(MAX_DATAGRAM_SIZE, max_datagram_size, uint16_t)                            \
   V(LAST_DATAGRAM_ID, last_datagram_id, datagram_id)                           \
   V(MAX_PENDING_DATAGRAMS, max_pending_datagrams, uint16_t)
@@ -2660,6 +2661,7 @@ void Session::SetApplication(std::unique_ptr<Application> app) {
   // without duplicating the per-application table.
   impl_->state()->no_error_code = app->GetNoErrorCode();
   impl_->state()->internal_error_code = app->GetInternalErrorCode();
+  impl_->state()->request_rejected_code = app->GetRequestRejectedCode();
   impl_->application_ = std::move(app);
 }
 
diff --git a/test/parallel/test-quic-h3-request-rejected.mjs b/test/parallel/test-quic-h3-request-rejected.mjs
new file mode 100644
index 00000000000..6ed987b395a
--- /dev/null
+++ b/test/parallel/test-quic-h3-request-rejected.mjs
@@ -0,0 +1,58 @@
+// Flags: --experimental-quic --no-warnings
+
+// An incoming HTTP/3 request stream that is rejected without any
+// application processing (here, the session has no stream consumer) is
+// reset with H3_REQUEST_REJECTED (0x10b) so the peer learns the request
+// was not processed. See RFC 9114 section 4.1.1.
+// Refs: https://github.com/nodejs/node/issues/65441
+
+import { hasQuic, skip, mustCall } from '../common/index.mjs';
+import assert from 'node:assert';
+import * as fixtures from '../common/fixtures.mjs';
+
+if (!hasQuic) {
+  skip('QUIC is not enabled');
+}
+
+const { listen, connect } = await import('node:quic');
+const { createPrivateKey } = await import('node:crypto');
+
+const key = createPrivateKey(fixtures.readKey('agent1-key.pem'));
+const cert = fixtures.readKey('agent1-cert.pem');
+
+// RFC 9114 H3_REQUEST_REJECTED.
+const H3_REQUEST_REJECTED = 0x10bn;
+
+// The server registers no stream consumer, so an incoming request stream
+// is rejected on arrival.
+const serverEndpoint = await listen(mustCall((serverSession) => {
+  serverSession.onerror = () => {};
+}), {
+  sni: { '*': { keys: [key], certs: [cert] } },
+});
+
+const clientSession = await connect(serverEndpoint.address, {
+  servername: 'localhost',
+  verifyPeer: 'manual',
+});
+await clientSession.opened;
+
+const reset = Promise.withResolvers();
+const stream = await clientSession.createBidirectionalStream({
+  headers: {
+    ':method': 'GET',
+    ':path': '/test',
+    ':scheme': 'https',
+    ':authority': 'localhost',
+  },
+});
+stream.onreset = mustCall((err) => {
+  assert.strictEqual(err.code, 'ERR_QUIC_APPLICATION_ERROR');
+  assert.strictEqual(err.errorCode, H3_REQUEST_REJECTED);
+  reset.resolve();
+});
+await assert.rejects(stream.closed, { code: 'ERR_QUIC_APPLICATION_ERROR' });
+
+await reset.promise;
+await clientSession.close();
+await serverEndpoint.close();